Placental hypoxia-regulating network in relation to birth weight and ponderal index: the ENVIRONAGE Birth Cohort Study

Placental hypoxia-regulating network in relation to birth weight and ponderal index: the ENVIRONAGE Birth Cohort Study

Abstract Background HIF1α, miR-210 and its downstream targets ISCU, COX-10, RAD52 and PTEN are all part of the placental hypoxia-responsive network. Tight regulation of this network is required to prevent development of maternal–fetal complications such as fetal growth restriction. HIF1α expression...

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Bibliographic Details
Main Authors: Karen Vrijens, Maria Tsamou, Narjes Madhloum, Wilfried Gyselaers, Tim S. Nawrot
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Translational Medicine
Subjects:
Birth weight
Gene expression
HIF1α
Hypoxia
Placenta
Online Access:http://link.springer.com/article/10.1186/s12967-017-1375-5

Internet

http://link.springer.com/article/10.1186/s12967-017-1375-5

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