Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies

Abstract The collection of known posttranslational modifications (PTMs) has expanded rapidly with the identification of various non-acetyl histone lysine acylations, such as crotonylation, succinylation and butyrylation, yet their regulation is still not fully understood. Through an unbiased chromat...

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Bibliographic Details
Main Authors: Leonie Kollenstart, Sophie C. van der Horst, Kees Vreeken, George M. C. Janssen, Fabrizio Martino, Hanneke Vlaming, Peter A. van Veelen, Fred van Leeuwen, Haico van Attikum
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91359-0