The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.

Despite progress in locoregional and systemic therapies, patient survival from lung cancer remains a challenge. Receptor tyrosine kinases are frequently implicated in lung cancer pathogenesis, and some tyrosine kinase inhibition strategies have been effective clinically. The EphB4 receptor tyrosine...

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Bibliographic Details
Main Authors: Benjamin D Ferguson, Ren Liu, Cleo E Rolle, Yi-Hung Carol Tan, Valery Krasnoperov, Rajani Kanteti, Maria S Tretiakova, Gustavo M Cervantes, Rifat Hasina, Robyn D Hseu, A John Iafrate, Theodore Karrison, Mark K Ferguson, Aliya N Husain, Leonardo Faoro, Everett E Vokes, Parkash S Gill, Ravi Salgia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699624?pdf=render