Perinatal Gene-Gene and Gene-Environment Interactions on IgE Production and Asthma Development

Atopic asthma is a complex disease associated with IgE-mediated immune reactions. Numerous genome-wide studies identified more than 100 genes in 22 chromosomes associated with atopic asthma, and different genetic backgrounds in different environments could modulate susceptibility to atopic asthma. C...

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Bibliographic Details
Main Authors: Jen-Chieh Chang, Lin Wang, Rong-Fu Chen, Chieh-An Liu
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/270869