Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation
Abstract Background Increasing evidence has proven that the γ-secretase complex plays significant roles in the carcinogenesis of malignancies. However, the independent effect of nicastrin (NCSTN), the largest constituent of the γ-secretase complex, on the progression of hepatocellular carcinoma (HCC...
Main Authors: | Xicheng Wang, Xining Wang, Yunxiuxiu Xu, Maolin Yan, Wenxin Li, Jie Chen, Tao Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
|
Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-020-01172-4 |
Similar Items
-
NCAPG Promotes The Proliferation Of Hepatocellular Carcinoma Through PI3K/AKT Signaling
by: Gong C, et al.
Published: (2019-10-01) -
ADORA1 Promotes Hepatocellular Carcinoma Progression via PI3K/AKT Pathway
by: Ni S, et al.
Published: (2020-12-01) -
Brucea javanica oil inhibits proliferation of hepatocellular carcinoma cells and induces apoptosis via the PI3K/AKT pathway
by: Yan-Peng Du, et al.
Published: (2021-03-01) -
ERCC6L promotes the progression of hepatocellular carcinoma through activating PI3K/AKT and NF-κB signaling pathway
by: Han Chen, et al.
Published: (2020-09-01) -
Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma
by: Junbin Liao, et al.
Published: (2019-11-01)