Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis

Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis

Abstract Background Condensation of chromatin prior to enucleation is an essential component of terminal erythroid maturation, and defects in this process are associated with inefficient erythropoiesis and anemia. However, the mechanisms involved in this phenomenon are not well understood. Here, we...

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Bibliographic Details
Main Authors: Nazish N. Jeffery, Christina Davidson, Scott A. Peslak, Paul D. Kingsley, Yukio Nakamura, James Palis, Michael Bulger
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Epigenetics & Chromatin
Subjects:
H2A.X
g-H2A.X
BAZ1B
WSTF
Chromatin condensation
Erythropoiesis
Online Access:https://doi.org/10.1186/s13072-021-00408-5

Internet

https://doi.org/10.1186/s13072-021-00408-5

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