Somatic point mutations in mtDNA control region are influenced by genetic background and associated with healthy aging: a GEHA study.

Somatic point mutations in mtDNA control region are influenced by genetic background and associated with healthy aging: a GEHA study.

Tissue specific somatic mutations occurring in the mtDNA control region have been proposed to provide a survival advantage. Data on twins and on relatives of long-lived subjects suggested that the occurrence/accumulation of these mutations may be genetically influenced. To further investigate contro...

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Bibliographic Details
Main Authors: Giuseppina Rose, Giuseppe Romeo, Serena Dato, Paolina Crocco, Amalia C Bruni, Antti Hervonen, Kari Majamaa, Federica Sevini, Claudio Franceschi, Giuseppe Passarino, GEnetics of Healthy Ageing Project Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954809?pdf=render

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http://europepmc.org/articles/PMC2954809?pdf=render

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