In Vitro and In Vivo Antitumor Activity of Cucurbitacin C, a Novel Natural Product From Cucumber

In Vitro and In Vivo Antitumor Activity of Cucurbitacin C, a Novel Natural Product From Cucumber

Cucurbitacin C (CuC), a novel analogue of triterpenoids cucurbitacins, confers a bitter taste in cucumber. Genes and signaling pathways responsive for biosynthesis of CuC have been identified in the recent years. In the present study, we explored the anti-cancer effects of CuC against human cancers...

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Bibliographic Details
Main Authors: Dinglan Wu, Zhu Wang, Muqi Lin, Yi Shang, Fei Wang, JiaYi Zhou, Xiantong Zhang, Xiaomin Luo, Weiren Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
cucurbitacin C
natural product
anti-cancer
growth arrest
apoptosis
Akt pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01287/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01287/full

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