Subcellular localization of alpha-synuclein aggregates and their interaction with membranes

Subcellular localization of alpha-synuclein aggregates and their interaction with membranes

For more than a decade numerous evidence has been reported on the mechanisms of toxicity of α-synuclein (αS) oligomers and aggregates in α-synucleinopathies. These species were thought to form freely in the cytoplasm but recent reports of αS multimer conformations when bound to synaptic vesicles in...

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Bibliographic Details
Main Authors: Fabiana Miraglia, Alessio Ricci, Lucia Rota, Emanuela Colla
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
alpha-synuclein; oligomers; aggregates; subcellular localization; membranes binding; Parkinson′s disease; neurodegeneration; alpha-synucleinopathies
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=7;spage=1136;epage=1144;aulast=Miraglia

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=7;spage=1136;epage=1144;aulast=Miraglia

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