A New Computational Model for Neuro-Glio-Vascular Coupling: Astrocyte Activation Can Explain Cerebral Blood Flow Nonlinear Response to Interictal Events.

Developing a clear understanding of the relationship between cerebral blood flow (CBF) response and neuronal activity is of significant importance because CBF increase is essential to the health of neurons, for instance through oxygen supply. This relationship can be investigated by analyzing multim...

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Bibliographic Details
Main Authors: Solenna Blanchard, Sandrine Saillet, Anton Ivanov, Pascal Benquet, Christian-George Bénar, Mélanie Pélégrini-Issac, Habib Benali, Fabrice Wendling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4743967?pdf=render