splitGFP Technology Reveals Dose-Dependent ER-Mitochondria Interface Modulation by α-Synuclein A53T and A30P Mutants
Familial Parkinson’s disease (PD) is associated with duplication or mutations of α-synuclein gene, whose product is a presynaptic cytosolic protein also found in mitochondria and in mitochondrial-associated ER membranes. We have originally shown the role of α-syn as a mod...
Main Authors: | Tito Calì, Denis Ottolini, Mattia Vicario, Cristina Catoni, Francesca Vallese, Domenico Cieri, Lucia Barazzuol, Marisa Brini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/9/1072 |
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