Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis.

Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis.

Canine Visceral Leishmaniasis (CVL) is a major veterinary and public health problem caused by Leishmania infantum (L. infantum) in many endemic countries. It is a severe chronic disease with generalized parasite spread to the reticuloendothelial system, such as spleen, liver and bone marrow and is o...

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Bibliographic Details
Main Authors: Mehdi Shahbazi, Farnaz Zahedifard, Tahereh Taheri, Yasaman Taslimi, Shahram Jamshidi, Sadegh Shirian, Niousha Mahdavi, Mehdi Hassankhani, Yahya Daneshbod, Sayyed Hamid Zarkesh-Esfahani, Barbara Papadopoulou, Sima Rafati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4509652?pdf=render

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http://europepmc.org/articles/PMC4509652?pdf=render

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