Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation

Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation

ObjectivePostoperative delirium (POD) is a common surgical complication in elderly patients. This study investigated the effects of dexmedetomidine on POD and pro-inflammatory markers in elderly patients with hip fracture.MethodsThis randomized, double-blind, controlled trial enrolled patients ≥65 y...

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Bibliographic Details
Main Authors: Wenchao Zhang, Tianlong Wang, Geng Wang, Minghui Yang, Yan Zhou, Yi Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
dexmedetomidine
elderly patients
hip fracture
pro-inflammatory factor
postoperative delirium
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00678/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00678/full

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