Cytokine/Chemokine Release Patterns and Transcriptomic Profiles of LPS/IFNγ-Activated Human Macrophages Differentiated with Heat-Killed <i>Mycobacterium obuense</i>, M-CSF, or GM-CSF

Cytokine/Chemokine Release Patterns and Transcriptomic Profiles of LPS/IFNγ-Activated Human Macrophages Differentiated with Heat-Killed <i>Mycobacterium obuense</i>, M-CSF, or GM-CSF

Macrophages (Mφs) are instrumental regulators of the immune response whereby they acquire diverse functional phenotypes following their exposure to microenvironmental cues that govern their differentiation from monocytes and their activation. The complexity and diversity of the mycobacterial cell wa...

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Bibliographic Details
Main Authors: Samer Bazzi, Emale El-Darzi, Tina McDowell, Helmout Modjtahedi, Satvinder Mudan, Marcel Achkar, Charles Akle, Humam Kadara, Georges M. Bahr
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Mycobacterium obuense</i>
immunomodulation
monocyte-derived macrophages
macrophage activation
RNA sequencing
Online Access:https://www.mdpi.com/1422-0067/22/13/7214

Internet

https://www.mdpi.com/1422-0067/22/13/7214

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