Basic helix-loop-helix transcription factor TCF21 is a downstream target of the male sex determining gene SRY.

The cascade of molecular events involved in mammalian sex determination has been shown to involve the SRY gene, but specific downstream events have eluded researchers for decades. The current study identifies one of the first direct downstream targets of the male sex determining factor SRY as the ba...

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Bibliographic Details
Main Authors: Ramji K Bhandari, Ingrid Sadler-Riggleman, Tracy M Clement, Michael K Skinner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3101584?pdf=render