TNF-α-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells

<p>Abstract</p> <p>Background</p> <p>Phosphatidylcholine (PC) is a major lipid of the gastrointestinal mucus layer. We recently showed that mucus from patients suffering from ulcerative colitis has low levels of PC. Clinical studies reveal that the therapeutic addition...

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Bibliographic Details
Main Authors: Griffiths Gareth, Füllekrug Joachim, Giese Thomas, Jeliaskova Petia, Braun Annika, Treede Irina, Stremmel Wolfgang, Ehehalt Robert
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/9/53