Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma: a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-κB, and TNF-α

Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma: a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-κB, and TNF-α

AIM: To find a new concept to show whether or not apoptosis of retinal ganglion cells (RGCs) can be determined in the histology of acute hyperglycemia in the role of expressed Brn3b gene related to nitric oxide (NO), caspase-3, nuclear factor kappa-B (NF-κB), and tumor necrosis factor-α (TNF-α) as a...

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Bibliographic Details
Main Authors: Irwan Tjandra, Purnomo Soeharso, Widya Artini, Nurjati Chairani Siregar, Andi Arus Victor
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2020-12-01
Series:International Journal of Ophthalmology
Subjects:
retinal ganglion cells
primary open angle glaucoma
brn3b
apoptosis
nitric oxide
caspase-3
nuclear factor kappa-b
tumor necrosis factor-α
Online Access:http://ies.ijo.cn/en_publish/2020/12/20201205.pdf

Internet

http://ies.ijo.cn/en_publish/2020/12/20201205.pdf

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