The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial

The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial

Background: Asymptomatic low-density gametocyte carriers represent the majority of malaria-infected individuals. However, the impact of recommended treatment with single low dose of primaquine and an artemisinin-based combination therapy to reduce transmission in this group is unknown. Methods: This...

Full description

Bibliographic Details
Main Authors: Joseph Okebe, Teun Bousema, Muna Affara, Gian Luca Di Tanna, Edgard Dabira, Abdoulaye Gaye, Frank Sanya-Isijola, Henry Badji, Simon Correa, Davis Nwakanma, Jean-Pierre Van Geertruyden, Chris Drakeley, Umberto D'Alessandro
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:EBioMedicine
Subjects:
Asymptomatic infection
Malaria
Primaquine
Plasmodium falciparum
Infectivity
Gametocyte carriage
Efficacy
Randomized trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416304935

Internet

http://www.sciencedirect.com/science/article/pii/S2352396416304935

Similar Items