Effects of Trandolapril on Structural, Contractile and Electrophysiological Remodeling in Experimental Volume Overload Heart Failure

Effects of Trandolapril on Structural, Contractile and Electrophysiological Remodeling in Experimental Volume Overload Heart Failure

Chronic volume overload induces multiple cardiac remodeling processes that finally result in eccentric cardiac hypertrophy and heart failure. We have hypothesized that chronic angiotensin-converting enzyme (ACE) inhibition by trandolapril might affect various remodeling processes differentially, thu...

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Bibliographic Details
Main Authors: Dagmar Jarkovská, Matúš Miklovič, Jitka Švíglerová, Luděk Červenka, Petra Škaroupková, Vojtěch Melenovský, Milan Štengl
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
cardiac remodeling
volume overload
aortocaval fistula
rat
renin-angiotensin-aldosterone system
trandolapril
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.729568/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.729568/full

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