Next-generation sequencing for BCR-ABL1 kinase domain mutation testing in patients with chronic myeloid leukemia: a position paper

Next-generation sequencing for BCR-ABL1 kinase domain mutation testing in patients with chronic myeloid leukemia: a position paper

Abstract BCR-ABL1 kinase domain (KD) mutation status is considered to be an important element of clinical decision algorithms for chronic myeloid leukemia (CML) patients who do not achieve an optimal response to tyrosine kinase inhibitors (TKIs). Conventional Sanger sequencing is the method currentl...

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Bibliographic Details
Main Authors: Simona Soverini, Elisabetta Abruzzese, Monica Bocchia, Massimiliano Bonifacio, Sara Galimberti, Antonella Gozzini, Alessandra Iurlo, Luigiana Luciano, Patrizia Pregno, Gianantonio Rosti, Giuseppe Saglio, Fabio Stagno, Mario Tiribelli, Paolo Vigneri, Giovanni Barosi, Massimo Breccia
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Hematology & Oncology
Subjects:
Next-generation sequencing
Chronic myeloid leukemia
Sanger sequencing
BCR-ABL1 mutation
Online Access:https://doi.org/10.1186/s13045-019-0815-5

Internet

https://doi.org/10.1186/s13045-019-0815-5

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