Together and apart: inhibition of DNA synthesis by connexin-43 and its relationship to transforming growth factor-beta
The membrane and channel protein Connexin-43 (Cx43), as well as the cytokine transforming growth factor (TGF) beta, suppress proliferative growth in cardiomyocytes and other cell types. Previously we showed that the inhibitory effect of Cx43 is cancelled when Cx43 becomes phosphorylated at serine (...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-07-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00090/full |