Synthesis, Antiproliferative Activity and Molecular Properties Predictions of Galloyl Derivatives

Synthesis, Antiproliferative Activity and Molecular Properties Predictions of Galloyl Derivatives

The present study was designed to investigate the in vitro antiproliferative activity against ten human cancer cell lines of a series of galloyl derivatives bearing substituted-1,3,4-oxadiazole and carbohydrazide moieties. The compounds were also assessed in an in silico study of the absorption, dis...

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Bibliographic Details
Main Authors: Marciane Maximo da Silva, Marina Comin, Thiago Santos Duarte, Mary Ann Foglio, João Ernesto de Carvalho, Maria do Carmo Vieira, Anelise Samara Nazari Formagio
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Molecules
Subjects:
galloyl
hydrazide
oxadiazole
antiproliferative activity
in silico study
Online Access:http://www.mdpi.com/1420-3049/20/4/5360

Internet

http://www.mdpi.com/1420-3049/20/4/5360

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