Spinocerebellar ataxia: miRNAs expose biological pathways underlying pervasive Purkinje cell degeneration

Spinocerebellar ataxia: miRNAs expose biological pathways underlying pervasive Purkinje cell degeneration

Recent work has demonstrated the importance of miRNAs in the pathogenesis of various brain disorders including the neurodegenerative disorder spinocerebellar ataxia (SCA). This review focuses on the role of miRNAs in the shared pathogenesis of the different SCA types. We examine the novel findings o...

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Bibliographic Details
Main Authors: Rogier van der Stijl, Sebo Withoff, Dineke S. Verbeek
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Neurobiology of Disease
Subjects:
miRNA
Spinocerebellar ataxia
Purkinje cells
Neurodegeneration
Cerebellum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117301882

Internet

http://www.sciencedirect.com/science/article/pii/S0969996117301882

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