Lipopolysaccharide-induced neuronal activation in the paraventricular and dorsomedial hypothalamus depends on ambient temperature.

Systemic inflammatory response syndrome is associated with either fever or hypothermia, but the mechanisms responsible for switching from one to the other are unknown. In experimental animals, systemic inflammation is often induced by bacterial lipopolysaccharide (LPS). To identify the diencephalic...

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Bibliographic Details
Main Authors: Samuel P Wanner, Kyoko Yoshida, Vladimir A Kulchitsky, Andrei I Ivanov, Kazuyuki Kanosue, Andrej A Romanovsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3777970?pdf=render