Vasoactive intestinal peptide ameliorates renal injury in a pristane-induced lupus mouse model by modulating Th17/Treg balance

Abstract Background Lupus nephritis (LN) is an inflammation of the kidneys and is a major cause of mortality in systemic lupus erythaematosus (SLE) patients. In addition, Th17/Treg balance is one of the most important factors that can promote the development of LN. It has been reported that vasoacti...

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Bibliographic Details
Main Authors: Dongdong Fu, Soulixay Senouthai, Junjie Wang, Yanwu You
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-019-1548-y