AQP4ex is crucial for the anchoring of AQP4 at the astrocyte end-feet and for neuromyelitis optica antibody binding

AQP4ex is crucial for the anchoring of AQP4 at the astrocyte end-feet and for neuromyelitis optica antibody binding

Abstract Brain water homeostasis is essential for the appropriate control of neuronal activity. Furthermore, the encasement of the central nervous system (CNS) by a hard structure, greatly limits its tolerance for the volume changes occurring with acute brain edema, which quickly leads to severe dam...

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Bibliographic Details
Main Authors: Claudia Palazzo, Cinzia Buccoliero, Maria Grazia Mola, Pasqua Abbrescia, Grazia Paola Nicchia, Maria Trojano, Antonio Frigeri
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Acta Neuropathologica Communications
Subjects:
Aquaporin-4
Astrocyte endfoot
Blood brain barrier
Orthogonal arrays of particles
OAPs,Translational readthrough
Neuromyelitis optica
Online Access:http://link.springer.com/article/10.1186/s40478-019-0707-5

Internet

http://link.springer.com/article/10.1186/s40478-019-0707-5

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