Tracing the evolution of the heterotrimeric G protein α subunit in Metazoa
Abstract Background Heterotrimeric G proteins are fundamental signaling proteins composed of three subunits, Gα and a Gβγ dimer. The role of Gα as a molecular switch is critical for transmitting and amplifying intracellular signaling cascades initiated by an activated G protein Coupled Receptor (GPC...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | BMC Evolutionary Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12862-018-1147-8 |