A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.

Multiple myeloma (MM) is a lethal human cancer characterized by a clonal expansion of malignant plasma cells in bone marrow. Mouse models of human MM are technically challenging and do not always recapitulate human disease. Therefore, new mouse models for MM are needed. Mineral-oil induced plasmacyt...

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Bibliographic Details
Main Authors: Peter O Hofgaard, Henriette C Jodal, Kurt Bommert, Bertrand Huard, Jo Caers, Harald Carlsen, Rolf Schwarzer, Nicole Schünemann, Franziska Jundt, Mona M Lindeberg, Bjarne Bogen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527494?pdf=render