Systematic Transcriptome Analysis of Noise-Induced Hearing Loss Pathogenesis Suggests Inflammatory Activities and Multiple Susceptible Molecules and Pathways

Systematic Transcriptome Analysis of Noise-Induced Hearing Loss Pathogenesis Suggests Inflammatory Activities and Multiple Susceptible Molecules and Pathways

Noise-induced hearing loss (NIHL) is characterized by damage to cochlear neurons and associated hair cells; however, a systematic evaluation of NIHL pathogenesis is still lacking. Here, we systematically evaluated differentially expressed genes of 22 cochlear samples in an NIHL mouse model. We perfo...

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Bibliographic Details
Main Authors: Quan Wang, Yilin Shen, Haixia Hu, Cui Fan, Andi Zhang, Rui Ding, Bin Ye, Mingliang Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Genetics
Subjects:
systematically evaluation
diagnostic value
NIHL pathogenesis
spiral ganglion neurons
functional annotation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00968/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00968/full

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