Persistent DNA damage after high dose in vivo gamma exposure of minipig skin.

BACKGROUND:Exposure to high doses of ionizing radiation (IR) can lead to localized radiation injury of the skin and exposed cells suffer dsDNA breaks that may elicit cell death or stochastic changes. Little is known about the DNA damage response after high-dose exposure of the skin. Here, we investi...

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Bibliographic Details
Main Authors: Emad A Ahmed, Diane Agay, Gerrit Schrock, Michel Drouet, Viktor Meineke, Harry Scherthan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3384646?pdf=render