Inhaled ambient-level traffic-derived particulates decrease cardiac vagal influence and baroreflexes and increase arrhythmia in a rat model of metabolic syndrome

Inhaled ambient-level traffic-derived particulates decrease cardiac vagal influence and baroreflexes and increase arrhythmia in a rat model of metabolic syndrome

Abstract Background Epidemiological studies have linked exposures to ambient fine particulate matter (PM2.5) and traffic with autonomic nervous system imbalance (ANS) and cardiac pathophysiology, especially in individuals with preexisting disease. It is unclear whether metabolic syndrome (MetS) incr...

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Bibliographic Details
Main Authors: Alex P. Carll, Samir M. Crespo, Mauricio S. Filho, Douglas H. Zati, Brent A. Coull, Edgar A. Diaz, Rodrigo D. Raimundo, Thomas N. G. Jaeger, Ana Laura Ricci-Vitor, Vasileios Papapostolou, Joy E. Lawrence, David M. Garner, Brigham S. Perry, Jack R. Harkema, John J. Godleski
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Particle and Fibre Toxicology
Subjects:
Particulate matter
Secondary organic aerosol
Baroreflex
Heart rate variability
Autonomic
Arrhythmia
Online Access:http://link.springer.com/article/10.1186/s12989-017-0196-2

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http://link.springer.com/article/10.1186/s12989-017-0196-2

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