Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells

Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells

Colorectal cancer (CRC) is the third leading malignant tumor in the world, which has high morbidity and mortality. In this study we found that trichodermic acid (TDA), a secondary metabolite isolated from the plant endophytic fungus <i>Penicillium ochrochloronthe</i> with a variety of bi...

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Bibliographic Details
Main Authors: Junyan Qu, Cheng Zeng, Tingting Zou, Xu Chen, Xiaolong Yang, Zhenghong Lin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
TDA
ER stress
apoptosis
autophagy
colorectal cancer
Online Access:https://www.mdpi.com/1422-0067/22/11/5566

Internet

https://www.mdpi.com/1422-0067/22/11/5566

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