Transactivation of PDGFRβ by dopamine D4 receptor does not require PDGFRβ dimerization

<p>Abstract</p> <p>Growth factor-induced receptor dimerization and cross-phosphorylation are hallmarks of signal transduction via receptor tyrosine kinases (RTKs). G protein-coupled receptors (GPCRs) can activate RTKs through a process known as transactivation. The prototypical mod...

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Bibliographic Details
Main Authors: Chi Sum, Vetiska Sandra M, Gill Robin S, Hsiung Marilyn S, Liu Fang, Van Tol Hubert HM
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/3/1/22