Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss.

BACKGROUND: In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance and organ dysfunction. However, several of the genes regulating adipose tissue...

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Main Authors: Simon N Dankel, Dag J Fadnes, Anne-Kristin Stavrum, Christine Stansberg, Rita Holdhus, Tuyen Hoang, Vivian L Veum, Bjørn Jostein Christensen, Villy Våge, Jørn V Sagen, Vidar M Steen, Gunnar Mellgren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2882947?pdf=render