Evaluating the Accuracy of Imputation Methods in a Five-Way Admixed Population

Genotype imputation is a powerful tool for increasing statistical power in an association analysis. Meta-analysis of multiple study datasets also requires a substantial overlap of SNPs for a successful association analysis, which can be achieved by imputation. Quality of imputed datasets is largely...

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Bibliographic Details
Main Authors: Haiko Schurz, Stephanie J. Müller, Paul David van Helden, Gerard Tromp, Eileen G. Hoal, Craig J. Kinnear, Marlo Möller
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00034/full