DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

The forebrain hemispheres are predominantly separated during embryogenesis by the interhemispheric fissure (IHF). Radial astroglia remodel the IHF to form a continuous substrate between the hemispheres for midline crossing of the corpus callosum (CC) and hippocampal commissure (HC). Deleted in color...

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Bibliographic Details
Main Authors: Laura Morcom, Ilan Gobius, Ashley PL Marsh, Rodrigo Suárez, Jonathan WC Lim, Caitlin Bridges, Yunan Ye, Laura R Fenlon, Yvrick Zagar, Amelia M Douglass, Amber-Lee S Donahoo, Thomas Fothergill, Samreen Shaikh, Peter Kozulin, Timothy J Edwards, Helen M Cooper, IRC5 Consortium, Elliott H Sherr, Alain Chédotal, Richard J Leventer, Paul J Lockhart, Linda J Richards
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
midline zipper glia
astrocyte morphology
agenesis of the corpus
callosum
deleted in colorectal cancer
telencephalic development
Online Access:https://elifesciences.org/articles/61769

Internet

https://elifesciences.org/articles/61769

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