CD36-deficient mice are resistant to alcohol- and high-carbohydrate-induced hepatic steatosis[S]

CD36-deficient mice are resistant to alcohol- and high-carbohydrate-induced hepatic steatosis[S]

CD36 is a scavenger receptor with multiple ligands and cellular functions, including facilitating cellular uptake of free fatty acids (FFAs). Chronic alcohol consumption increases hepatic CD36 expression, leading to the hypothesis that this promotes uptake of circulating FFAs, which then serve as a...

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Bibliographic Details
Main Authors: Robin D. Clugston, Jason J. Yuen, Yunying Hu, Nada A. Abumrad, Paul D. Berk, Ira J. Goldberg, William S. Blaner, Li-Shin Huang
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Journal of Lipid Research
Subjects:
alcoholic steatosis
de novo lipogenesis
fatty acid uptake
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520350318

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http://www.sciencedirect.com/science/article/pii/S0022227520350318

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