Correlation between 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) uptake and expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter 1 (LAT1) in primary prostate cancer

Correlation between 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) uptake and expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter 1 (LAT1) in primary prostate cancer

Abstract Purpose To evaluate the expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter1 (LAT1) in prostate cancer (PCa) and their impact on uptake of 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) which is approved for the detection of re...

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Bibliographic Details
Main Authors: Irena Saarinen, Ivan Jambor, Mai Kim, Anna Kuisma, Jukka Kemppainen, Harri Merisaari, Olli Eskola, Anna-Riina Koskenniemi, Ileana Montoya Perez, Peter Boström, Pekka Taimen, Heikki Minn
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:EJNMMI Research
Subjects:
18F-fluciclovine
Amino acid transporter
ASCT2
LAT1
Prostate cancer
PET
Online Access:http://link.springer.com/article/10.1186/s13550-019-0518-5

Internet

http://link.springer.com/article/10.1186/s13550-019-0518-5

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