Dopamine neuron dependent behaviors mediated by glutamate cotransmission

Dopamine neuron dependent behaviors mediated by glutamate cotransmission

Dopamine neurons in the ventral tegmental area use glutamate as a cotransmitter. To elucidate the behavioral role of the cotransmission, we targeted the glutamate-recycling enzyme glutaminase (gene Gls1). In mice with a dopamine transporter (Slc6a3)-driven conditional heterozygous (cHET) reduction o...

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Bibliographic Details
Main Authors: Susana Mingote, Nao Chuhma, Abigail Kalmbach, Gretchen M Thomsen, Yvonne Wang, Andra Mihali, Caroline Sferrazza, Ilana Zucker-Scharff, Anna-Claire Siena, Martha G Welch, José Lizardi-Ortiz, David Sulzer, Holly Moore, Inna Gaisler-Salomon, Stephen Rayport
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
glutaminase
amphetamine sensitization
latent inhibition
motivational salience
resilience model
schizophrenia
Online Access:https://elifesciences.org/articles/27566

Internet

https://elifesciences.org/articles/27566

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