Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics

Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics

Summary: Nuclear factor κB (NF-κB) RelA is the potent transcriptional activator of inflammatory response genes. We stringently defined a list of direct RelA target genes by integrating physical (chromatin immunoprecipitation sequencing [ChIP-seq]) and functional (RNA sequencing [RNA-seq] in knockout...

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Bibliographic Details
Main Authors: Kim A. Ngo, Kensei Kishimoto, Jeremy Davis-Turak, Aditya Pimplaskar, Zhang Cheng, Roberto Spreafico, Emily Y. Chen, Amy Tam, Gourisankar Ghosh, Simon Mitchell, Alexander Hoffmann
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720301522

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http://www.sciencedirect.com/science/article/pii/S2211124720301522

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