CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy

CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy

<p>Abstract</p> <p>Background</p> <p>The ubiquity of protein-protein interactions in biological signaling offers ample opportunities for therapeutic intervention. We previously identified a peptide, designated CBD3, that suppressed inflammatory and neuropathic behaviora...

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Bibliographic Details
Main Authors: Piekarz Andrew D, Due Michael R, Khanna May, Wang Bo, Ripsch Matthew S, Wang Ruizhong, Meroueh Samy O, Vasko Michael R, White Fletcher A, Khanna Rajesh
Format: Article
Language:English
Published: SAGE Publishing 2012-07-01
Series:Molecular Pain
Subjects:
Peptide
Excitability
Nociception
AIDS therapy-induced chronic pain
Calcium channels
Molecular dynamics
Online Access:http://www.molecularpain.com/content/8/1/54

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http://www.molecularpain.com/content/8/1/54

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