Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes

Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes

Trichloroethylene (TCE) and inorganic arsenic (iAs) are environmental contaminants that can target the kidney. Chronic exposure to TCE is associated with increased incidence of renal cell carcinoma, while co-exposure to TCE and iAs likely occurs in exposed human populations, such as those near Super...

Full description

Bibliographic Details
Main Authors: Amie Perry, Rachel M. Lynch, Ivan Rusyn, David W. Threadgill
Format: Article
Language:English
Published: Oxford University Press 2019-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
renal toxicity
trichloroethylene
arsenic
environmental exposure
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400161

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400161

Similar Items