Liraglutide improves lipid metabolism by enhancing cholesterol efflux associated with ABCA1 and ERK1/2 pathway

Liraglutide improves lipid metabolism by enhancing cholesterol efflux associated with ABCA1 and ERK1/2 pathway

Abstract Background Reverse cholesterol transport (RCT) is an important cardioprotective mechanism and the decrease in cholesterol efflux can result in the dyslipidemia. Although liraglutide, a glucagon like peptide-1 analogue, has mainly impacted blood glucose, recent data has also suggested a bene...

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Bibliographic Details
Main Authors: Ya-Ru Wu, Xiao-Yun Shi, Chun-Yan Ma, Yue Zhang, Rui-Xia Xu, Jian-Jun Li
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cardiovascular Diabetology
Subjects:
Liraglutide
db/db mice
High-fat diet
Reverse cholesterol transport
High glucose
ABCA1
Online Access:http://link.springer.com/article/10.1186/s12933-019-0954-6

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http://link.springer.com/article/10.1186/s12933-019-0954-6

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