Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity

Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity

Abstract Background Amorphous silica nanoparticles (SiO2 NPs) have been regarded as relatively benign nanomaterials, however, this widely held opinion has been questioned in recent years by several reports on in vitro and in vivo toxicity. Surface chemistry, more specifically the surface silanol con...

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Bibliographic Details
Main Authors: Laura Rubio, Georgios Pyrgiotakis, Juan Beltran-Huarac, Yipei Zhang, Joshi Gaurav, Glen Deloid, Anastasia Spyrogianni, Kristopher A. Sarosiek, Dhimiter Bello, Philip Demokritou
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Particle and Fibre Toxicology
Subjects:
Silanol groups
Amorphous silica
Surface reactivity
Flame spray pyrolysis
Toxicity
Online Access:http://link.springer.com/article/10.1186/s12989-019-0325-1

Internet

http://link.springer.com/article/10.1186/s12989-019-0325-1

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