Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice

Cancer immunotherapy: Improving animal models Improvements to mouse models for cancer immunotherapy could enhance the precision of new drugs. Immunotherapy trials require genetically modified animal models, including ‘humanized’ mice with a functioning human immune system, and patient-derived xenogr...

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Bibliographic Details
Main Authors: Yunsik Choi, Sanghyuk Lee, Kapyoul Kim, Soo-Hyun Kim, Yeun-Jun Chung, Charles Lee
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0115-0