Circular permutation prediction reveals a viable backbone disconnection for split proteins: an approach in identifying a new functional split intein.

Circular permutation prediction reveals a viable backbone disconnection for split proteins: an approach in identifying a new functional split intein.

Split-protein systems have emerged as a powerful tool for detecting biomolecular interactions and reporting biological reactions. However, reliable methods for identifying viable split sites are still unavailable. In this study, we demonstrated the feasibility that valid circular permutation (CP) si...

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Bibliographic Details
Main Authors: Yun-Tzai Lee, Tz-Hsiang Su, Wei-Cheng Lo, Ping-Chiang Lyu, Shih-Che Sue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427171?pdf=render

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http://europepmc.org/articles/PMC3427171?pdf=render

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