Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair

Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair

Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation. Long term, it is associated with acute rejection and chronic graft dysfuncti...

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Bibliographic Details
Main Authors: Gertrude J. Nieuwenhuijs-Moeke, Søren E. Pischke, Stefan P. Berger, Jan Stephan F. Sanders, Robert A. Pol, Michel M. R. F. Struys, Rutger J. Ploeg, Henri G. D. Leuvenink
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Journal of Clinical Medicine
Subjects:
ischemia reperfusion injury
kidney transplantation
delayed graft function
innate immune system
adaptive immune system
apoptosis
necrosis
hypoxic inducible factor
endothelial dysfunction
Online Access:https://www.mdpi.com/2077-0383/9/1/253

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https://www.mdpi.com/2077-0383/9/1/253

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