Abundance of clinical variants in exons included in multiple transcripts
Abstract Previous studies showed that the magnitude of selection pressure in constitutive exons is higher than that in alternatively spliced exons. The intensity of selection was also shown to be depended on the inclusion level of exons: the number of transcripts that include an exon. Here, we exami...
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| Format: | Article |
| Language: | English |
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BMC
2018-06-01
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| Series: | Human Genomics |
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| Online Access: | http://link.springer.com/article/10.1186/s40246-018-0166-2 |