Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

<p>Abstract</p> <p>Background</p> <p>Studies have shown the existence of p21 induction in a p53-dependent and -independent pathway. Our previous study indicates that DOX-induced p65 is able to bind the p21 promoter to activate its transactivation in the cells.</p>...

Full description

Bibliographic Details
Main Authors: Zhou YingQi, Li Gang, Ji Yuan, Liu Chen, Zhu JingPing, Lu YanJun
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Journal of Biomedical Science
Subjects:
p21
p65
p53
DOX
Online Access:http://www.jbiomedsci.com/content/19/1/15