Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

Summary: The structural and functional plasticity of synapses is critical for learning and memory. Long-term potentiation (LTP) induction promotes spine growth and AMPAR accumulation at excitatory synapses, leading to increased synaptic strength. Glutamate initiates these processes, but the contribu...

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Bibliographic Details
Main Authors: Faye McLeod, Alessandro Bossio, Aude Marzo, Lorenza Ciani, Sara Sibilla, Saad Hannan, Gemma A. Wilson, Ernest Palomer, Trevor G. Smart, Alasdair Gibb, Patricia C. Salinas
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718304959

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http://www.sciencedirect.com/science/article/pii/S2211124718304959

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